منابع مشابه
Nonsmooth Regularization in Electrocardiographic Imaging
Electrocardiographic imaging is an inverse problem which consists of computing epicardial potential distributions from measurements of body surface potentials. Smoothing and attenuation of the electric field by the intervening body volume conductor render the problem ill posed, requiring regularization to stabilize the inverse solution. This paper reports a study on the efficacy of nonsmooth re...
متن کاملAssessment of regularization techniques for electrocardiographic imaging.
A widely used approach to solving the inverse problem in electrocardiography involves computing potentials on the epicardium from measured electrocardiograms (ECGs) on the torso surface. The main challenge of solving this electrocardiographic imaging (ECGI) problem lies in its intrinsic ill-posedness. While many regularization techniques have been developed to control wild oscillations of the s...
متن کاملClinical Implementation of Electrocardiographic Imaging (ecgi): Design, Development, and Verification of a Person-specific Electrocardiographic Imaging System
by DAVID CHARLES KAELBER The inverse problem in electrocardiography is the noninvasive reconstruction of epicardial potentials, electrograms, and activation isochrones from measured body surface potentials. The goal of clinical inverse solutions is to image the electrical activity on the epicardial surface of the in vivo heart, noninvasively. Despite advances in the theory and techniques of inv...
متن کاملNoninvasive electrocardiographic imaging of arrhythmogenic substrates in humans.
Cardiac excitation is determined by interactions between the source of electric activation (membrane depolarization) and the load that cardiac tissue presents. This relationship is altered in pathology by remodeling processes that often create a substrate favoring the development of cardiac arrhythmias. Most studies of arrhythmia mechanisms and arrhythmogenic substrates have been conducted in a...
متن کاملCardiac repolarization: insights from mathematical modeling and electrocardiographic imaging (ECGI).
Cardiac repolarization is a complex rate dependent process. At the cellular level, it depends on a delicate dynamic balance of ion channel currents. At the heart level, it is spatially heterogeneous, leading to spatial gradients of potential and excitability. This article provides insights into the molecular mechanisms of the delayed rectifiers I(Kr) (rapid) and I(Ks) (slow) that underlie effec...
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ژورنال
عنوان ژورنال: Circulation
سال: 1998
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.97.15.1496